Vinpocetine may aid men

April 15, 2005

An enzyme named phosphodiesterase type 5 is elevated in the vas deferens of men with premature ejaculation. The vas deferens are muscular tubes involved with ejaculation. It was found that Vinpocetine helps inhibit the phosphodiesterase type 5 enzyme which then allows the walls of the vas deferens to relax and this activity may be helpful for men with premature ejaculation. It is the only nondrug treatment mentioned. The review is published in the February 2005 issue of the journal Molecular Human Reproduction.

Vinpocetine may help women with urinary urge incontinence according to a number of studies and reviews

Women with urge incontinence require treatment that relaxes the bladder. As it turns out, Vinpocetine is the only nondrug treatment mentioned for urge incontinence. With stress incontinence strengthening of the pelvic floor and external sphincter is needed and estrogenic substances are mentioned, and with overflow incontinence alpha-blockers are mentioned. The review appears in the March 2005 issue of the German journal, Des Urologe AUSG A.

The common side effects and limited clinical efficacy of many drugs used for urge incontinence has spurred a search for more selective, less toxic compounds. Vinpocetine, a selective inhibitor of phosphodiesterase enzymes, may help patients who do not respond to tandard anticholinergic drug therapy. Vinpocetine may also help with other bladder issues and interstitial cystitis.The results of a larger randomized, double-blind, placebo-controlled multicenter trial with Vinpocetine, at probably too low a dosage, shows that it has clinical efficacy. The study and review is published in the World Journal of Urology.

Pomegranate may protect the skin from the suns UVB radiation

The suns ultraviolet B radiation causes sunburn, excess pigment discoloration of the skin, suppression of the immune system, excessive growth of skin cells, aging of the skin, and skin cancer. Pomegranate contains unique ingredients including the anthocyanin polyphenols delphinidin, cyaniding, and pelargonidin, and the tannin polyphenols punicalin, pedunculagin, punicalagin, gallagic and Ellagic acid esters that possess powerful antioxidant, and anti-inflammatory properties. Recently these researchers demonstrated that pomegranate has anticancer effects protecting lab animals from cancer causing chemicals (carcinogens). Pre-treating one day before UVB exposure decreased the release of genes that cause damage to healthy skin cells and inhibited inflammation of healthy skin tissue. The conclusion is that Pomegranate extract protects skin from UVB radiation damage and aging. The research was conducted at the Department of Dermatology, University of Wisconsin and is published in the Jan-Feb issue of the journal Photochemistry and Photobiology.