In a study of patients who suffered an ischemic stroke 7 patients were given a daily intravenous
infusion without Vinpocetine and six were given the same infusion but with the addition of Vinpocetine
for 14 days in a double-blind study. A pet scan was used along with transcranial doppler parameters
to measure the effectiveness of the treatments. Blood flow throughout the brain improved with the
addition of Vinpocetine, while the ability to use glucose, the chief substrate for energy production
improved in particular, but important regions of the brain. The ability to use glucose for energy
production improved significantly in the thalamus and the caudate neuleus, and cerebral blood flow
improved throughout the brain but more significantly so in these areas with a 36% improvement in the
flow of blood in the thalamus and a 37% improvement in the caudate neucleus. The study shows that a
two week course of treatment with intravenous Vinpocetine improves blood flow throughout the brain
after an ischemic stroke and especially improves it in the thalamus and the caudate neucleus. The
distrubution of glucose for energy use also improves but in this study, in particular brain regions.
The study is published in the March 2005 issue of the Journal of Neurological Sciences.
Commentary by Jerry Hickey, R.Ph.
The caudate nucleus helps control voluntary movements involving large limbs (e.g. adjusting
the arm so the fingers can pick something up), it also regulates and organizes information being
sent to the brain. The thalamus regulates sensory input and motor control. It is important for
sight, hearing, taste, smell, touch, temperature recognition, balance, pain, pleasure, arousal,
control of movement, muscle control and sensing the bodies relationship to its physical
environment. This was a short study and a longer study probably would demonstrate even greater
benefit. I take 10mg of Vinpocetine almost every morning and notice improved brain energy and
efficiency on the days I take it.
Both Green and Black Tea Polyphenols inhibit lung cancer in lab animals
Tea polyphenols have been shown by different researchers to inhibit lung cancer in different
animal models. This includes lung cancer caused by different cancer causing chemicals including
some of those more troublesome ones found in pollution and in tobacco smoke. The te ingredients
reduced the number and size of tumors and even in the number of animals that developed lung
cancer. The Green Tea polyphenol EGCG, and the Black Tea polyphenol Theaflavins have both been
shown to be effective. The Black Tea preparations have reduced thhe number of animals with
cancer and the number of lung tumors in mice, and also inhibited the transformation of lung
adenomas to adenocarcinoma. In Green Tea it is the EGCG that is effective. In many experiments,
the consumption of tea preperations resulted in the reduction of body fat and body weight, and
this factor may also contribute to the decreased risk of lung canmcer. The review was performed
at the Susan Lehman Cullman Laboratory for Cancer research , Ernest Mario School of Pharmacy,
Rutgers University, and is published in the January-February 2005 issue of the journal
Experimental Lung Research.
New and powerful way that Green Tea's EGCG inhibits cancer discovered
Scientists at both the University of Murcia in Spain, and the John Innes Center in England
have found a powerful way that the most important Green Tea Polyphenol, EGCG fights an existing
cancer. EGCG inhibits the enzyme dihydrofolate reductase (DHFR). DHRF is a recognized and
established target for cancer chemotherapeutic drugs, and this may be the first study showing
that Green tea's EGCG targets the same cancer site as established drugs, except without the
toxicity and this is in addition to the other targets EGCG has for reducing the risk of developing
and also fighting a cross section of cancers. Targetting DHFR is the same way that the commonly
used chemotherapeutic drug methotrexate works. The study is publsihed in the current issue of
the journal Cancer Research.
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