Ultrasound gives proof that GliSODin protects the walls of arteries
April
08,
2008
French researchers used a high definition ultrasound to evaluate the level of
plaque on the walls of the carotid arteries. These arteries are critical and
supply the head and brain with blood and oxygen. The patients enrolled in the
study were high risk for developing cardiovascular disease; they smoked, or
were obese, and had high blood pressure. They ranged in age between 30 and 60.
A group of these high risk patients were given GliSODin. The supplement improved
the thickness of the carotid artery lining in both the intima and media layers
demonstrating a protective effect for the cardiovascular system. The study is
published in the February 2007 issue of journal Allergy and immunology.
Turmeric has been clinically studied in a wide array of illnesses with successful
results
Turmeric supplying Curcumin has antioxidant, anti-inflammatory and anti-cancerous
effects. In phase I human clinical studies it has been used in doses as high
as 3600mg to 8000mg daily for 4 months without toxicity. The effects of Turmeric
were studied in patients with rheumatoid arthritis, inflammatory eye diseases,
inflammatory bowel diseases, chronic pancreatitis, psoriasis, hyperlipidemia
(high levels of blood fats), and with various cancers. The preliminary results
supported the efficacy of Turmeric in these diseases in these clinical studies.
The study review is published in Advances in Experimental Medicine and Biology,
2007;595.
Curcumin may be an attractive addition to the treatment of ovarian
cancer even when chemotherapy works poorly
Nutrition News; Scientists at the School of Medical sciences, RMIT University
in Victoria Australia have analyzed the green lipped muscle known as Perna Canaliculus,
and have discovered that it contains 3 newly discovered, novel, omega 3 fatty
acids that have significant anti-inflammatory activity. The research is published
in the April 2007 issue of Comparative Biochemistry and Physiology. Part B,
Biochemistry and Molecular Biology.
Researchers at the Department of Gynecological Oncology, the University of Texas
M.D. Anderson Cancer Center note that Curcumin from Turmeric has been shown
to suppress inflammation and the improper formation of new blood vessels that
feed tumors largely by suppressing the immune system component known as NF-kappa
B.
In their new study Curcumin was added to various forms of ovarian cancer either
in the laboratory or implanted in animals. The Curcumin was given either alone
or in conjunction with the chemotherapeutic drug docetaxel (Taxotere). Docetaxel
is a taxane drug just like paclitaxel (Taxol). Some animals were left untreated
as a control group to measure effectiveness of the herb and drug.
In the laboratory study, Curcumin inhibited NF-kappa B and suppressed cancer
cell growth. In the animals, large doses of Curcumin inhibited NF-kappa B and
suppressed factors that promote the creation of a blood supply that nourishes
the cancerous tumor.
In two different cell types of ovarian cancer in the animals, Curcumin used
alone strongly reduced average tumor growth by 49% and 55%. When Curcumin was
combined with docetaxel it significantly and strongly reduced the average growth
of the same tumors by 96% and 77%. When used in animals with chemotherapy drug
resistant ovarian cancer Curcumin alone reduced the average tumor growth by
a significant 47%, and when both agents were used the chemotherapy resistant
cancers average growth was inhibited by 58%.
Based on significant effectiveness in preclinical models, Curcumin-based therapies
may be attractive in patients with ovarian cancer. The study is published in
the June 1st, 2007 issue of Clinical Cancer Research, an official journal
of the American Association for Cancer Research.
Curcumin from Turmeric has a great influence on many skin conditions
Scientists at the Uniformed Services, University of Health Sciences in Bethesda
state that Curcumin, the active compound derived from the herb Turmeric has
many different activities and is very safe even when given at higher doses.
There is existing data showing its benefit for skin diseases including use for
scleroderma, psoriasis, and skin cancer. It works in many ways including as
a potent antioxidant and it also reduces inflammation.
Curcumin reduces the healing time of wounds, enhancing healing in both normal
and impaired wound-healing (as in a diabetic). The studies reviewed suggest
the beneficial effects of Curcumin and the potential of this compound to be
developed as a potent nontoxic agent for treating skin diseases. It is also
an attractive agent for further research in treating tumors of the colon, duodenum,
pancreas and breast. The research review is published in Advances in Experimental
Medicine and Biology, 2007;595.
Curcumin ameliorates many autoimmune diseases
The immune system has evolved to protect us from infection; nevertheless, a
breakdown in the immune system often results in cancer, infection, and autoimmune
diseases. An autoimmune disease occurs when our own immune system misidentifies
a part of our own body and attacks it resulting often in a dangerous, even sometimes
fatal outcome. Multiple sclerosis, rheumatoid arthritis, type 1 diabetes, inflammatory
bowel diseases, myocarditis, thyroiditis, uveitis, lupus, and myasthenia gravis
are organ-specific autoimmune diseases that afflict more than 5% of the population
worldwide.
The use of herbal supplements is on the rise in patients with autoimmune diseases,
mainly because they are effective, inexpensive and relatively safe. Curcumin
from the herb Turmeric has traditionally been used for pain and wound-healing.
Recent studies have shown that Curcumin ameliorates multiple sclerosis, rheumatoid
arthritis, psoriasis, and inflammatory bowel disease. In human or animal studies
Curcumin helps by regulating chemical messengers that control or provoke the
immune system. The research review was performed by scientists at the Neuroscience
Research Laboratory, Methodist research Institute in Indianapolis, and is published
in Advances in Experimental Medicine and Biology, 2007;595.
Protection from acute and chronic lung disease by Curcumin
Scientists at the Faculty of Medicine, UMR-7561, Vandoeuvre les Nancy, France
crunched data from studies examining the benefits of Curcumin from the herb
Turmeric in treating sudden-acute or chronic-longstanding lung diseases. Occupational
and environmental exposures to mineral dusts, airborne pollutants, cigarette
smoke, chemotherapy, and radiotherapy (radiation) injure the lungs, resulting
in lung diseases.
Although major advances have been made in treating lung diseases, no drug treatment
modifies the condition. Current drug therapy offers only marginal benefit. Over
the years, there has been increasing evidence that Curcumin from the herb Turmeric,
has a wide spectrum of therapeutic properties, and a remarkable range of protective
effects in various diseases. Several experimental animal models have found that
Curcumin reduces lung injuries and scarring (fibrosis) caused by radiation,
chemotherapeutic drugs, and toxins. The growing pile of data from pharmacological
and animal studies also shows that Curcumin plays a therapeutic or protective
role in COPD, acute lung injury, acute respiratory distress syndrome (a fatal
condition where the lungs air sacs fill with blood and fluid making breathing
difficult), and allergic asthma. Curcumin’s therapeutic action is due
to antioxidant and anti-inflammatory activity. The review is published in Advances
in Experimental Medicine and Biology, 2007;595.
Curcumin protects the kidneys and liver
Curcumin from Turmeric has a wide spectrum of therapeutic effects including
antitumor, anti-inflammatory, antibacterial, antiviral, antifungal, and antispasmodic
activity. Curcumin is changed into metabolites that can protect the kidneys
and improve creatinine and urea clearance. Curcumin also protects the kidneys
from toxic chemicals and has an antioxidant, anti-inflammatory effect in the
kidneys. These metabolites, especially tetrahydrocurcumin (or THU1- one of the
things the body changes Curcumin into) help protect diabetics from developing
kidney damage and nerve damage.
In the liver, Curcumin helps protect from drugs, cancer causing chemicals, mold
in foods, and solvents, reducing the risk of DNA damage and possibly even liver
cancer. Curcumin may even protect the liver from the toxic effects of alcohol.
The research review was performed at Nagoya University Graduate School of Bioagricultural
Sciences in Japan and is published in Advances in Experimental Medicine
and Biology, 2007;595.