NF-Kappa B is a messenger chemical released in your body. Releasing
NF-Kappa B controls genes that cause inflammation. This inflammation
causes cellular damage and allows the proliferation of cancerous
tumor cells. Proliferation is the increase in number of tumor cells
because the cells are allowed to grow and multiply. Studies show
that non-steroidal anti-inflammatory drugs inhibit this activity
and decrease the risk of particular cancers.
In this study, researchers compared 12 agents that help control
inflammation. The agents included aspirin, prescription and
nonprescription drugs, even corticosteroids, chemotherapy, and
List of agents tested:
Ibuprofen (Advil, Motrin)
Sulindac (Clinoril - prescription)
Phenylbutazone (Butazolidin - prescription)
Indomethacin (Indocin - prescription)
Diclofinac (Voltaren - prescription)
Dexamethasone (steroid - prescription)
Tamoxifen (Chemotherapy - prescription)
All of these agents inhibited the proliferation of tumor cells.
The natural remedies Resveratrol and Turmeric were much stronger
than the other 8 agents (although ibuprofen came close to them in
protective activity). The Turmeric and Resveratrol matched the
effectiveness of Celebrex. Amazingly, they were very-very close in
protective activity to the strongest agent, the chemotherapy drug
tamoxifen, but without the dangerous side effects and toxicity. The
study appears in the October 18th, 2004 issue of the journal
Arthritis Drugs Have Cancer Fighting Ability
Arthritis drugs inhibit inflammation by blocking the COX-2 enzyme.
According to this new research, blocking the COX-2 enzyme may help
fight cancer. Researchers at Cedars-Sinai Medical Center in Los
Angeles announced on Friday that these drugs may have the ability
to improve the immune systems capability of attacking brain tumors
other tumors. The COX-2 enzyme disrupts the immune systems
ability to properly defend us from tumors, allowing cancer cells to
thrive and multiply. Accordingly, blocking the COX-2 enzyme boosts
the immune systems ability to identify, target, and attack cancer
According to lead researcher, Dr. John Yu, when the COX-2 enzyme
is secreted it shuts down proper immune function in the brain
preventing the brains immune system from tracking and attacking
brain tumors. Dr. Yu hopes to incorporate use of COX-2 inhibitors
with all brain cancer patients. The study is published in the
October 1st issue of the journal Immunology.
Elderly Latina Women Risk Depression if Low in Folic Acid
883 Latina women aged 60 or older were checked for Folic Acid
status and also for symptoms of depression in the Sacramento Area
Latino Study on Aging (SALSA). High scores for depression were
correlated with the lowest blood levels of folic acid. The study
is published in the October 2004 issue of The American Journal
of Clinical Nutrition.
It is Harder to Absorb Calcium as Women Get Older
It has been assumed that Calcium absorption becomes more difficult
with age. In this study 262 healthy postmenopausal women aged 40
to 87 years of age were checked for the absorption of calcium and
the relationship of calcium absorption to age, vitamin D status,
and other factors. The researchers used radioactively-tagged
calcium for tracking purposes. It was found that calcium absorption
decreased by 28% in the 25 women aged 75 or older vs. the younger
women. The study is published in the October 2004 issue of The
American Journal of Clinical Nutrition.
Commentary by Jerry Hickey, R.Ph.
The suggested level of daily calcium intake for women over the age
of 75 is 1,500mg per day. Perhaps it should be a little bit higher.
If there is a 28% decreased rate of absorption that means 1,080mg
will be absorbed for every 1,500mg of elemental calcium consumed.
To bring this up to an absorption level of 1,200mg a woman over
the age of 75 would have to consume almost 1,700mg of elemental
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