When you have a scan of your bones it tells you that you have lost bone and that
you have developed the bone thinning conditions known as osteoporosis or the
milder-earlier version known as osteopenia; bone thinning increases your risk of
fracture. However, you cannot tell from the test if the bone loss is occurring
now or has occurred previously. To find out if you are currently loosing bone
your doctor will look at the level of deoxypyridinolone (Dpyr) in your urine.
Dpyr is released from the bone when it is breaking down so a higher level shows
that your bone loss is getting worse. Conversely, if the level drops then the
therapy you are using to build bone is working.
In this review of existing studies, scientists only included those studies that
were placebo-controlled and randomized and that monitored the level of Dpyr in
the urine. Nine trials fit the selection criteria which included 432 people. If
the study subjects consumed Soy Isoflavones, even at less than 90mg a day for as
little as 12 weeks the level of Dpyr dropped significantly in the urine and
markers in the blood that signify the building of bone also increased compared
to placebo. The study is published on-line ahead of print in the European
Journal of Clinical Nutrition.
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