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Recent human studies have demonstrated the benefits of a vitamin with nutraceutical formulation supplying Folate, vitamin B6, alpha-tocopherol vitamin E, SAMe, NAC and ALCAR for patients with Alzheimer's disease at mild to moderate stages. The researchers have now tested this formulation for effect in a small cohort of 12 institutionalized patients diagnosed with moderate-stage to later-stage Alzheimer's disease.
Participants were randomly separated into either a nutritional treatment group or a placebo group. Participants receiving the formulation demonstrated a clinically significant delay in decline in the Dementia Rating Scale and clock-drawing test as compared to those receiving placebo. Institutional caregivers reported approximately 30% improvement in the Neuropyschiatric Inventory and maintaining better performance in daily living for more than 9 months.