Sulforaphane Halts Breast Cancer Cell Growth

November 08, 2004

Sulforaphane is a very important phytochemical found in the cabbage family. This compound has a potent ability to induce protective detoxifying enzymes that provide defense against dangerous cancer causing chemicals. Researchers have discovered that Sulforaphane can halt breast cancer cells in their tracks and have identified a new mechanism explaining Sulforaphane's anticancer ability. The article appears in the November 1st, 2004 issue of Drug Discovery Today.

Estradiol Protects Cervical Cancer Cells from Chemotherapy and Radiation: Indole-3-Carbinol reverses this Effect

Many tumors are dependent on estrogen for growth, and estrogen also shields these tumors from chemotherapy. In three different types of cervical cancer cells, estradiol protected the cancer from the chemotherapeutic agents mitomycin-C, cisplatin, and also from radiation. It also partially protected the cancer cells from Taxol. Indole-3-Carbinol is a nontoxic phytochemical extracted from cabbage vegetables. Indole-3-Carbinol has the ability to prevent human papiloma virus associated cervical cancer. Estradiol was able to block this cancer-preventing effect of Indole-3-Carbinol, but increasing the dosage of Indole-3-Carbinol overcame the ability of estradiol to protect the cervical cancer cells. The study is published in the September-October 2004 issue of the journal Anticancer Research.

Rhodiola Rosea Extract Protects Muscle During Exercise and Lowers Inflammation

Healthy, untrained volunteers were put through an exhausting exercise regime. Rhodiola Rosea extract decreased levels of inflammatory C-reactive protein and protected muscle during the exercise regime. The study is published in the July 2004 issue of the Bulletin of Experimental Biology and Medicine.

Lutein and Zeaxanthin may Decrease Eye Damage from Glaucoma

Researchers initiated glaucoma in laboratory animals (Guinea pigs). Before the experiment the eye pressure in group I was 16.8 and after causing the disease it rose to 26.2 mm Hg. The eye pressure in group II was 16.5 and rose to 25.9 mmHg. Group I was placed on Lutein and Zeaxanthin, group II was not given these carotenoids. The animals supplemented with carotenoids lost 18.9% of their retinal ganglion cells (nerve tissue) and the animals not given the carotenoids lost 29.7% of these important vision cells. The nerve damage in the un-supplemented animals spread to surrounding tissue. The study was published in the journal Oftalmologia 2003;59(4):70-5.