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Statin Drugs lower cholesterol but also make it go rancid; adding Coenzyme Q10 and Vitamin E prevent this negative effect

Jul 14, 2006



43 patients with coronary artery disease and high cholesterol were placed on a statin drug to lower their LDL-cholesterol. The statin drug used was a generic version of Zocor (simvastatin) prescribed at a dosage of 20mg a day. Some of the patients were placed on 30mg of Coenzyme Q10 and vitamin E along with the statin. The drug did effectively lower LDL-cholesterol in almost two thirds of the patients at this dosage but it also increased the lipid peroxidation of LDL by up to almost 30%. When the LDL becomes damaged like this it becomes rancid and contributes to coronary heart disease. It was found that giving the Coenzyme Q10 plus vitamin E along with the medication significantly decreased the oxidizing effect of the statin drug on LDL. The study is published in the current issue of the European journal Clinical Medicine.

Commentary by Jerry Hickey, R.Ph.

Studies show it is not the caffeine which helps decrease the risk of developing diabetes but probably the polyphenols.