SAMe Added to Antidepressant Medication Has Great Benefit in Drug Resistant Depression

December 03, 2004

SAMe was supplemented to 30 people who were still struggling with depression while on SSRI antidepressant medication such as Prozac, Paxil, and Effexore. Within 6 weeks 50% of the patients reported great improvemnet in the depression when adding SAMe to the drug therapy. 43% reported having no depression left at all, at the six week point after adding SAMe to their medication therapy. The study is published in the December 2004 issue of the Journal of Clinical Psychophamacology.

Chlorophyllin Causes Human Colon Cancer Cells to Die

Chlorophyllin is a water soluble derivative of chlorophyll. It is an anti-cancer and anti-mutation agent. It has already been reported to cause the death of colon cancer cells by causing the cells to differentiate, when cells differentiate into what they are supposed to be (in this case healthy colon tissue), control is restored to the tissue and the body regains ability to fight a tumor.

In this new study colon cancer tissue was treated with chlorophyllin. In colon cancer, a protein is released called B-catenin. B-catenin causes the inhibition of a tumor suppressing gene that would obviously help control colon tissue and prevent colon cancer activity. Adding chlorophyllin to the colon tissue caused the B-catenin to move out of the cell nucleus allowing the reinstitution of tumor-fighting, tumor-preventing activity by the colon tissue. The study is published in the December 2004 issue of the Journal of Nutrition, a journal of the American Society for Nutritional Sciences

Both Genesteine and Grape Seed Extract Prevented Breast Cancer in Mice, but only with a Good Diet

DMBA is a chemical that causes breast cancer. Four months after feeding the rats DMBA, Grape Seed Extract was added to dry chow. The Grape Seed Extract cut the multiplicity of breast cancer tumors by 50%.

In N-Methyl-N-Nitrosurea induced breast cancer, adding Genesteine cut the number of breast cancer tumors by 44% to 61%.

Neither agent was effective when the rats were on a poor diet low in Selenium, Vitamin E, Vitamin K, Vitamin B12, lacking the minerals Silicon, Molybdenum, Boron, and Vanadium, low in essential fatty acids, and high in sugar and corn oil.

The study was a joint effort by the University of Alabama, and Purdue University at the University of Alabama and is published in the December 2004 issue of the Journal of Nutrition.

Indole-3-Carbinol Has Benefit in Fighting and Preventing Prostate Cancer

These researchers have previously shown that Indole-3-Carbinol (I3C) causes prostate cancer cells to stop their growth cycle and I3C causes prostate cancer cells to die.

They have also shown that I3C and its metabolite DIM increase the detoxification and removal of dangerous chemicals and hormones that can cause cancer.

I3C and DIM regulate genes that control the cell, its growth cycle, its ability to reproduce, and the ability of cells to communicate properly with one another (better communication among cells also blocks the cancer cycle).

They now have found that I3C decreases prostate cancer cell survival, and its ability to withstand chemotherapy. In chemotherapy resistant prostate cancer (the late stage of androgen resistant prostate cancer) I3C improves the ability of chemotherapy to kill these cells. In conclusion the researchers state there is ample evidence that I3C and its metabolite DIM have benefit for the prevention and treatment of prostate cancer. The research was performed at the Department of Pathology, Kanmanos Cancer Insitute, Wayne State University School of Medicine in Detroit Mi., and is published in the December 2004 issue of the Journal of Nutrition.