Researchers from the Medical College of Wisconsin supplemented NAC to cocaine addicts at a dose of 1200mg to 2400mg a day for 4 days. In just this short time NAC produced a significant reduction in craving by restoring brain health to these subjects, In a lead-in study feeding cocaine addicted rats NAC inhibited their abuse of cocaine and the effect persisted in the short time studied. Plasticity refers to the adaptability of the brain.

    Research shows that the supplement NAC reduces the risk of using cocaine in people treated for cocaine abuse and interferes with their need for cocaine. NAC seems to achieve this at least in part by controlling glutamate related stimulatory activity in the brain. In this small study 23 cocaine users who were seeking treatment were supplemented with NAC at a dosage of 1200mg a day, 2400mg a day, or 3600mg a day for four-weeks by researchers at the Center for Drug and Alcohol Programs, Department of Psychiatry, Medical University of South Carolina.

    53 healthy men were supplemented with 150mg of Ubiquinol daily for two-weeks because recent research indicates that Ubiquinol affects genes including those involved with cholesterol levels. Average Coenzyme Q10 plasma levels increased by 4.8-fold within this short period. Ubiquinol affected genes of immune cells involved with inflammation and cell differentiation (this reduces cancer risk).

Patients with elevated blood pressure (Stage 1 Hypertension with a systolic reading ranging from 143 to 155 and a diastolic reading ranging from 89 to 99) were placed on either the prescription drug Captopril (an ACE inhibiting drug used to treat high blood pressure) at a dose of 12.5 to 25mg twice a day or Olive Leaf at a dose of 500mg twice a day for eight weeks. The study was a double-blind, randomized, parallel and active-controlled clinical study. Additionally, this study also investigated the hypolipidemic (blood fat) effects of Olive leaf extract in the patients.