BRCA1 and BRCA2 are genes that control the growth of cells and suppress tumor growth. If there is damage to these genes then the risk of breast, ovarian, and prostate cancer increase significantly. The BRCA2 gene if damaged is also related to pancreatic cancer and possibly colon cancer.

A patient with pancreatic cancer that had metastasized to the liver was told by a reputable university oncology center in October 2002 that there was little hope for his survival. The patient visited an integrative medical department and was put on a combination of intravenous Alpha-Lipoic Acid and low dose naltrexone along with a healthy lifestyle program. Today, January 2006, he is back at work, free from symptoms, and without appreciable progression of his malignancy.

In this study, Green Tea Extract was given to 70 modestly obese individuals for 3 months. The average body mass index, a measure of body fat, was 28.9% at enrollment into the study. The patients consumed a total of 270mg EGCG daily divided into two servings.

The same risk factors that increase the chances of developing cardiovascular disease, including high cholesterol, high homocysteine, high blood pressure, and a high level of inflammation, increase the risk of dementia including its most common form, Alzheimer's disease. High cholesterol is also associated with an elevated level of beta-amyloid protein, the hallmark of Alzheimer's disease. Free radical damage (oxidative damage) is a major factor in the development of cardiovascular disease and dementia, both of which are diseases whose risk increases with age.

Coffee has several metabolic effects that help reduce the risk of type 2 diabetes. In a study of 12,287 individuals, a group of who were aged 45 to 64, after an overnight fast received the standard glucose tolerance test. In an additional 2,434 subjects fasting and postprandial glucose and blood sugar were taken and compared to coffee consumption.