Possible Problem with Prostate Radioactive Seed Implant
Radioactive Iodine containing tiny seeds are implanted in the
prostate to treat prostate cancer. Researchers at the Cleveland
Clinic Foundation were performing routine tests to check for
possible radioactive seed migration to other parts of the body.
Since late in 2001, 23,184 seeds were implanted in the 246 patients
who were evaluated. Of these, 75 seeds were found in the urine,
and 25 migrated to the thorax. However, in this possibly unique
case, the seeds in the prostate became damaged, the radioactive
Iodine escaped and migrated to the patient's thyroid gland. The
amount found in the thyroid was not enough to be clinically
important according to the researchers, however radioactive Iodine
can damage the thyroid gland and decrease the metabolic rate. The
case report is published in the November 2004 issue of the Journal
Both "Mini Stroke" and Stroke Should be Viewed as Brain Attack
In this very important study researchers compared 1,380
patients admitted to a hospital for a transient ischemic
attack (TIA) to 3,855 patients hospitalized with a full
blown stroke. A TIA is a shorter version of a stroke where
the brain attack (like a heart attack) is of shorter duration;
the duration of decreased blood flow in the brain is briefer.
In comparing the two groups during their hospital stay it
was found that 2% of the TIA patients had a cardiovascular
event versus 4% in the stroke population, and 8% of the TIA
patients actually developed a subsequent stroke during their
8% of TIA patients and 19% of stroke patients developed either
pneumonia or a urinary tract infection.
2% of the TIA patients died during their hospital stay,
versus 9% of the stroke patients. > 5% of the TIA patients
died versus 10% of the stroke patients in the following six
months after they were first admitted.
5% of TIA patients had a stroke within the following six
months and 6% of the stroke patients suffered an additional stroke.
In the opinion of the researchers both TIA and strokes should
be considered brain attacks and both groups of patients should be
evaluated similarly. The report appears in the November 2004 issue
of the journal Stroke.
Meta Analysis Shows that NAC Protects the Kidneys During Heart Test
When cardiologists test the heart muscle and surrounding blood vessels
they use a radioactive contrast media given by injection to give a better
picture on the X-ray. Unfortunately, a common effect of this contrast
media is kidney damage.
In this meta-analysis of 5 trials that included patients with existing
kidney damage who were placed on NAC in double-blind, placebo-controlled
studies it was found that NAC decreased kidney damage by 20%, and that
there was a 70% decreased risk in contrast induced kidney disease.
The study is published in the November 2004 issue of the journal