Invite Health Podcast, Episode hosted by Jerry Hickey. Ph
What is cannabidiol? It’s an ingredient in the hemp plant that has a number of benefits. But hemp is a very complex plant; everyone knows about the cannabidiol - sometimes abbreviated as CBD
- but scientists have already isolated 113 different phytocannabinoids in hemp. They seen, that when used together, they amplify the benefits of the hemp
What is the Entourage effect?
When you look at Green tea, for example, it has a very important component known as EGCG. This has been shown to be good for the brain, your heart, your bones and helping build muscle when you exercise, helping burn fat. But there are at least 19 other ingredients found in the green tea leaf that resemble EGCG that, when combined, the benefits are amplified. This is the same with the hemp plant. You focus on the cannabidiol
but you get that entourage effect of all of the other phytocannabinoids and you can expect better results.†
What can you expect from Hemp?
Hemp seems to reboot your brain, helping with stress, mood, focus, appetite control, and overall brain wellness in the daytime but also improving sleeping patterns at night. Scientists are looking at how Hemp, if full spectrum, can calm you down, help with anxiety, and possibly reduce chronic pain. A lot of this has to do with your amygdala. The amygdala is two small clusters of cells in the grey matter of your brain. The amygdala is located in the core of the brain, close to the centers for memory. As an example, if you break your leg and move it after, the pain you feel is supposed to alert you that you can further damage your leg. If you dont move it, you are not supposed to have as much pain. In fact, when they put you in a cast, the pain is basically gone. So it seems that chronic pain for the most part is a learned experience that seems to occur in the amygdala. It is also linked to fear and pleasure.†
There is new research saying that if you can sidetrack the amygdala, the experience of chronic pain starts to lessen. Researchers are finding out that cannabidiol seems to help you do this a lot quicker. The anygdala is linked to conditions such as anxiety, depression, post-traumatic stress disorder, and phobias are increasingly being linked to abnormal functioning of the amygdala. It seems that cannabidiol with the entourage of phytocannabidols reboots your amygdala and helps get rid of all of those negative responses.†
How does cannabidiol work?
In the body, there are CB-2 receptor sites that have to do with pain and inflammation. In the brain, there are CB1 receptor sites and they are in parts of the brain involved with memory, learning and controlling your emotions. When you take cannabidiol, it doesnt actually attach to CB1 or CB2 receptor sites, it prompts them to work properly. It seems to help restore balance in the human body
. Hemp is good for the brain; the phytocannabinoids are great antioxidants and also serve to help reduce inflammation; you never want inflammation in the brain.†
Is Hemp safe?
First of all, it’s not psychoactive (it’s not THC); Marijuana is the recreational product that is used for its psychoactive effects, or "getting high". This is not hemp. Hemp is used for pain and brain issues including for the aging brain. Hemp actually helps keep the brain alert, healthy, and in good working order. There has to be less than 0.3% THC in the product according to the Farm Bill that was passed as law in 2018. Hemp is demonstrating that it is extremely safe. The dosage of CBD used in children with certain types of epilepsy is much, much stronger than what you could get from any supplement. Ingredients from Hemp are also sold as a nasal spray to help reduce nerve pain in patients with MS; these are vulnerable people demonstrating the safety aspects of hemp.†
How do you take it?
In pharmacy, we are always focused on pharmacokinetics, which is how something is absorbed. There are many different options, from a capsule, to a tincture to rubbing it on your skin through a topical. CBD oil is fatty soluble; take it with food and it will work a lot better because you will absorb a great deal more.†
Topical hemp products really helps with pain; knee pain, sciatica, and back pain. If it is for your back or muscles or nerve pain try to get a CBD that also contains menthol. As a pharmacist, I would call Menthol an anodyne - it has a cooling effect and when applied externally it helps reduce pain. If it is for inflamed skin such as red, itchy skin, or a rash, you don’t need the menthol so get a soothing type roll on perhaps; Hemp is a great anti-inflammatory on the skin.†
Thank you for tuning in to the Invite Health Podcast. You can find all of our episodes for free wherever you listen to podcasts or by visiting www.invitehealth.com/podcast. Make sure you subscribe and leave us a review! Follow us on Facebook, Twitter and Instagram at Invite Health today. We’ll see you next time on another episode of the Invite Health Podcast.