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In a placebo controlled clinical trial adults were given different doses of plant phytosterols to gauge their effects on cholesterol. The diet supplied 50mg of phytosterols. Adding 400mg of phytosterols per day decreased their cholesterol very slightly, decreased the absorption of cholesterol from their food by 10% and increased the level of cholesterol excreted by 36%. Supplementing the diet with 2000mg of Sterols decreased serum LDL-cholesterol by a significant 9%, decreased the absorption of cholesterol from the diet by 25% and improved the excretion of cholesterol by 74%. The research was performed at Washington University School of Medicine and it is published in the January 2010 issue of the American Journal of Clinical Nutrition.