In this study 60 patients from different centers with painful osteoarthritis of the hip or knee
were given a Perna Canaliculus (New Zealand green lipped muscle) regimen twice a day and were
assessed at 4 and again at 8 weeks: the end of the study. Perna Canaliculus significantly improved
the signs and symptoms of osteoarthritis as determined by all measures. At 4 weeks, 53% of the
patients experienced significant pain relief and improvement of joint function, and at 8 weeks the
figure rose to 80% of all patients. The study was published in the June 2003 issue of the journal
Allergy and Immunology.
Perna Canaliculus alleviates signs of arthritis in dogs
The study was to assess the ability of Perna Canaliculus (green lipped mussel) to alleviate the
signs of arthritis in dogs. 31 Mixed breed dogs with arthritis were given either dried chow, or
dried chow with Perna added to it in a random, double-blind study. The degree of arthritis was
evaluated according to the degree of pain in a joint, amount of swelling, crepitus (e.g. the
grinding noise of the joint), and its range of motion. After the end of the study (six weeks total)
there was a significant decrease in total arthritis score in the Perna-chow group of digs. There
were significant improvements in joint pain, joint swelling, in the Perna-chow group vs. the control
group (chow only). These findings provide strong evidence that Perna Canaliculus can help alleviate
arthritis symptoms in pets. The study is published in the winter 2003 issue of the journal
Veterinary Therapeutics.
Perilla Frutescens Extract inhibits seasonal allergic rhinoconjunctivitis in humans
In this 21 day, randomized, placebo-controlled clinical trial, patients with seasonal allergies
that cause symptoms in the eyes and nose were given either 200mg a day of Perilla frutescens extract,
or 50mg a day, or a placebo. The patients were given blood tests, and nasal secretion samples were
examined during the study and patients recorded their symptoms daily in a diary. The Perilla
Frutescens significantly decreased the level of symptoms including itchy nose, watery or itchy eyes,
and total symptoms. The nasal lavage fluid of the patients on Perilla Frutescens had far fewer
allergy associated cells (neutrophils and eosinophils).The study was published in the March 2004
issue of the journal Experimental Biology and Medicine.
