NAC and Folic Acid lower dangerous homocysteine levels and improve blood vessel function in patients with coronary artery disease

February 08, 2008

In patients with coronary artery disease (CAD) a high level of homocysteine in the blood is a cause of clogging of the arteries, heart attack and stroke. In this new study 60 patients with CAD were given either inactive placebo, 5 mg of Folic Acid or 600 mg of NAC daily for eight-weeks. The function of blood vessel walls (their ability to open) was measured by highly sensitive ultrasound (high resolution ultrasound). Folic Acid decreased homocysteine from 21 on average to 12.5 on average. NAC decreased homocysteine from 20.9 to 15.6 within the same timeframe. Both nutrients improved the ability of the blood vessels to function properly and open up in response to blood flow needs; both of course possibly related to the percentage drop in homocysteine. The placebo had none of these effects. The study is published in the December 2007 issue of the journal Acta Cardiologica; a major European cardiology journal.