NAC + EGCG add up to much greater lung cancer fighting ability in this cell study
February
11,
2008
The nutrient NAC has cancer preventing activities especially in the lungs, colon,
and bladder and in animal models it also fights existing cancerous tumors and
protects against the toxic side-effects of various chemotherapeutic drugs. EGCG
(green teas major antioxidant) has well known cancer preventing and cancer fighting
activity.
In this new study NAC was added to EGCG to see if it would improve its ability
to fight lung cancer. The more NAC added to lung cancer cells that were already
being treated with EGCG, the greater the ability of the Green Tea Extract to
kill the cancerous cells. In fact, adding NAC to EGCG increased the ability
of EGCG to kill human lung cancer cells by 880% compared to treatment by either
agent alone. NAC increased the ability of EGCG to penetrate the cancer cells.
As it turns out giving both EGCG and NAC together actually created a new cancer
fighting molecule “EGCG-2”-NAC” and it took time for this
combination to form. The green tea ingredient EGCG actually attached to NAC
to form a new agent never seen before and this new combination may enhance the
effects of EGCG in fighting and killing cancer cells. The study was performed
at the Ernest Mario School of Pharmacy at Rutgers and is published on line ahead
of print in the journal Free Radical Biology and Medicine.
Radiation exposure may cause thymus gland lymphoma and Turmeric may
prevent it
Radiation is a well known cancer causing agent. In this study scientists at
Bhabha Atomic Research Center have proven that exposing mice to radiation (whole
body exposure) over a three or four week period causes thymic lymphoma (TL).
The more days elapsed after radiation exposure the more common the incidence
of lymphoma; after 90 days 47% of the mice developed cancer but by 150 days
post exposure 93% of the mice developed lymphoma. Female mice developed cancer
somewhat more frequently than male mice the same age and their cancers were
larger and more aggressive. The incidence of lymphoma decreased in older mice
especially in male mice. Giving the mice Turmeric high in Curcumin decreased
the incidence of lymphoma by 55% and Vitamin C decreased the incidence of lymphoma
by 20%. The study is published in the Journal of Environmental Pathology,
Toxicology and Oncology, 2007;26(4).