High Dose Green Tea helps prevent the formation of colorectal polyps in at risk patients

January 06, 2011

     Colorectal cancer is rarely an isolated event. For many patients with colorectal cancer, there is an increased risk for developing secondary complications, repeat cancerous events, commonly referred to as metachronous colorectal cancer. In many cases, the colon experiences additional cases of polyp development before the first case of colorectal cancer is even in remission.

     Epidemiological evidence shows that drinking greater than ten cups of Green Tea per day decreases the risk of colorectal cancer in Japanese individuals. Colorectal adenomas (polyp) are the precursors to most colorectal cancers. Researchers from Gifu University Graduate School of Medicine conducted a randomized controlled clinical trial to determine if Green Tea Extract supplements can prevent the formation of metachronous colorectal adenomas (polyps) by increasing Green Tea consumption from an average of six-cups per day to greater than ten-cups a day by supplementing the six-cups with a Green Tea tablet.

     The researchers recruited 136 patients who had surgery to remove colorectal polyps and had a follow up colonoscopy one year later and were confirmed to have no additional polyps.71 of these patients had a Green Tea supplement added to their intake of 6 cups of Green Tea per day for one-year and 65 patients just drank their six-daily cups of Green Tea with no additional supplement and these were labeled the Control Group.

     An additional year later the patients received another follow-up colonoscopy. 31% of the patients in the Control Group had developed polyps but only 15% in the Green Tea Supplement Group. Also, the polyps that did occur in the Green Tea Supplement Group were smaller. The study is published in the November 2008 issue of the journal Cancer Epidemiology, Biomarkers and Prevention.