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A botanical ointment containing a Green Tea Extract supplying its powerful antioxidants is an effective and well tolerated treatment for external genital and anal warts, results of a controlled study confirm. "Green tea catechins exert multiple biologic activities, involving potent antiviral and antioxidant activity," Dr. Silvio Tatti notes in the journal Obstetrics and Gynecology. Given that genital and anal warts are caused by human papillomavirus (HPV) and that effective, well tolerated treatments are lacking, there has been interest in treatment with Green Tea Catechin ointments.
In their study, Tatti's team randomly assigned 502 adults with 2 to 30 warts to either Green Tea Catechin ointment (15% or 10%) or inactive ointment for up to 16 weeks or until the warts cleared. In both Catechins groups, warts cleared completely in roughly 57% of patients compared to just 34% of subjects in the control group - a significant difference. Clearance rates of at least 50% were seen in roughly three-quarters of patients who applied Green Tea Catechin ointment compared with 51% of those who applied the inactive ointment. Most side effects reported with Catechin ointment were mild to moderate skin and application site reactions. The results support the use of Green Tea Catechin ointment for external warts, Tatti and colleagues conclude. The study is published in the June 2008 issue of the journal Obstetrics and Gynecology.