Grape Seed OPC inhibits colon cancer cells

December 13, 2005

Oligomeric proanthocyanidins are the very powerful antioxidants derived from grape seeds and they are usually referred to as OPC. OPC seep into the liver and kidneys, and are very protective in these organs. OPC also protect the lungs, brain, and digestive tract. Grape seed OPC protect connective tissue by inhibiting enzymes that degrade it, and help protect the eyes and vision. OPC are thought to have anti-cancer activities.

In this study colorectal cancer cells were exposed to OPC and it was found that the greater the concentration of OPC the greater was the ability to kill the cancer cells. The level of cancer cell cellular executioners called Caspase-3 cells were significantly increased by the presence of OPC and the levels of factors that fight cancer improved. The study is published in the August 14th, 2005 issue of the World Journal of Gastroenterology.

Commentary by Jerry Hickey, R.Ph.

At the start of this study the impact of the supplements Green Tea Extract and CLA were not even thought of yet - studies show these both impact weight.

Research review demonstrates the benefits of Vinpocetine after a stroke

The Apocynaceae family of plants contains a wide assortment of alkaloids that have pharmacological activity on the brain. These alkaloids improve brain circulation, balance nerve activity, while protecting the brain from a lack of oxygen and other stressful conditions. Chief among these is Vinpocetine, a safe derivative of an alkaloid from the lesser periwinkle plant. Vinpocetine improves electrolyte-energy function in the brain, connects with the benzodiazepine receptor to aid stress and anxiety, and protects the brain from glutamate (an excitotoxin). Vinpocetine is clinically useful after an ischemic stroke and for vascular conditions of the brain. Positron emission tomography shows that Vinpocetine is functional throughout the brain and it also concentrates in the basal ganglia, thalamus, and visual cortex areas of both the human and primate brain. These areas are involved with visual input and translating what you are viewing, in deciphering information from your senses, and in movement. Vinpocetine is also active in areas of the brain involved with memory and learning. Vinpocetine improves blood flow in areas damaged during a stroke and improves the utilization of energy in the brain from its main source of fuel - glucose. The literature-research review is published in the November issue of the journal Medical Research Reviews.