Grape Seed Extract shrinks colon cancer tumors in this study

January 26, 2007

Scientists at the School of Pharmacy, University of Colorado at Denver studied the effects of Grape Seed Extract (GSE) against colorectal cancer. In the first part of the study, exposing various colon cancer cell lines to GSE slowed the growth of colon cancer cells and also caused the cancer cells to die.

In the second part of the study mice lacking immune function were given human colon cancer in a surgical procedure called a xenograft. High doses of Grape Seed Extract shrunk the size of the cancerous tumors by 44% after 8 weeks of treatment without causing any toxicity. The GSE both inhibited cell growth and caused the death of the cancer cells within the tumor. The study is published in the October 15th, 2006 issue of the journal Clinical Cancer Research.

UC Davis study shows that Grape Seed Extract effective for lowering blood pressure; results prompt second UC Davis clinical trial

Grape Seed Extract lowered the blood pressure of patients with metabolic syndrome who had high blood pressure according to the UC Davis cardiovascular researchers. The patients were riddled with health concerns including high cholesterol, elevated blood glucose, being overweight and of course suffering with high blood pressure. The one month study included twenty-four patients who had their pressure monitored for the next twelve hours each day after supplementation. Giving the patients from 150mg to 300mg of Grape Seed Extract daily decreased their blood pressure by 12 points on the systolic or upper figure and by 8 points on the diastolic or lower figure in their blood pressure reading. The study?s lead researcher C T Kappagoda, professor of cardiovascular medicine and director of the Preventive Cardiology Program at UC Davis states that patients who were supplemented with 300mg of GSE also saw a stabilization of their LDL-cholesterol; it was less likely to turn rancid and contribute to heart disease progression. Three previous studies in animal models by this team have indicated that GSE may also prevent hardening of the arteries. The findings were presented at the March 26th 2006, American Chemical Society Meeting in Atlanta. For more on these studies visit the UC Davis Health System website.