Scientists from the Research Institute of Public Health, Kuopio, Finland state
that enterolactone (the major Lignan derived from Flaxseed) reduces the risk
of stroke, heart attack, and cancer. Because of this prior research they checked
the level of enterolactone in 1889 men aged 42 to 60 and followed them for over
12 years on average. The higher the level of enterolactone in the serum of these
men the lower the risk of dying from coronary heart disease or other forms of
cardiovascular disease. Enterolactone is what flaxseed lignans are changed into
in our body. The study is published in the May 2003 issue of the journal Archives
of Internal Medicine; a journal of the American Medical Association.
Lignans help prevent hypertension in older women
Scientists at the University Medical Center, Utrecht, the Netherlands, compared
the intake of Lignans and blood pressure in 301 postmenopausal women. The scientists
found that with increasing intake of plant Lignans there was a corresponding
drop in systolic and diastolic blood pressure readings with a decrease in the
risk of developing high blood pressure. Even at low levels of intake Lignans
improved blood pressure and helped prevent hypertension. The study is published
in the July 2004 issue of the Journal of Hypertension.
Flaxseed has the potential to decrease breast cancer tumor growth
Flaxseed is the richest source of mammalian lignans and it has previously been
shown to reduce the growth of tumors in rats. This study examines, in a randomized
double-blind, placebo controlled clinical trial, the effects of dietary flaxseed
on breast cancer markers in postmenopausal women with newly diagnosed breast
Researchers at Princess Margaret Hospital, University of Toronto gave 19 newly
diagnosed women 25g of Flaxseed in a muffin and 13 women a placebo muffin for
a little over a month. Tumor tissue was examined for the rate of cell growth
and other important pathological factors at the time of diagnosis and again
at the time of surgery. Lignan levels increased dramatically in the women on
Flaxseed. The women on the Lignans had a decrease in breast cancer cell proliferation.
Markers indicating a poor prognosis and resistance to treatment dropped when
on the Lignan source and the Flax also caused breast cancer tumor cells to die.
In conclusion the Flaxseed Lignan source has the potential to reduce tumor growth
in patients with breast cancer. The study is published in the May 15th 2005
issue of Clinical Cancer Research.
Flaxseed Lignans protect brain function in older women
In this study 394 healthy, postmenopausal women on a Western diet had their
mental health and intake of lignans and isoflavones examined. Using sophisticated
testing techniques the researchers found that a higher intake of lignans was
tied into better cognitive function and better mental performance. The protection
was even more pronounced for women who were 20 to 30 years postmenopausal. The
research was performed at the Julius Center for Health Sciences and Primary
Care, University Center, Utrecht, the Netherlands and is published in the May
2005 issue of the Journal of Nutrition.
Flax Lignans improve hair loss in men
Androgenic alopecia (AGA) is the most common form of hair loss in both men and
women. In AGA there is too high a level of the powerful male hormone DHT. DHT
enters into the hair follicle and sends a signal for the follicle to miniaturize;
the hair that then grows is thinner, brittle and likely to fall out. DHT also
sends a signal to stop hair growth and eventually no hair will grow at all from
The enzyme that converts testosterone to DHT is called 5-alpha reductase. Therefore
if you can inhibit this enzyme the level of DHT will drop. Doing this in the
follicle will slow the loss of hair and according to some studies eventually
will allow the signal for hair growth to start again.
In this pilot study by researchers from the Netherlands, a small group of men
with AGA were given 50mg of flax lignans daily for six-months from a high Lignan
flax complex capsule. 80% of the men had modest improvement in hair loss and
10% had a great improvement; the effects were noticed within one or two months.
The study is available through Acatris.Com.
Flaxseed with Lignans in conjunction with a low fat diet significantly slows
the growth of the prostate, lowers PSA, and reduces cholesterol’
Scientists at the Division of Urologic Surgery, Duke University Medical Center,
undertook a pilot study to examine the effects of a flaxseed supplemented, fat
restricted diet on men with BPH. Fifteen men who were scheduled to undergo repeat
prostate biopsy followed the Flaxseed supplemented diet for six-months. At the
six-month point their was a statistically significant drop in their PSA level
of about 3 points, a 28 point drop in total cholesterol on average, and a significant
inhibition of the growth of prostate cells. In fact some of the men no longer
required follow-up biopsies because their PSA levels returned to normal. The
study is published in the May 2004 issue of the journal Urology.
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