Combining Acetyl-L-Carnitine with Alpha-Lipoic Acid improves high blood pressure

April 24, 2007

The mitochondria are the power plants of your cells; this is where energy is created. When the mitochondria create energy they produce free radicals (unstable-cell damaging substances) that contribute to blood vessel dysfunction. Acetyl-L-Carnitine (ALCAR) and Alpha-Lipoic Acid (ALA) soak up these free radicals and improve mitochondrial function. In this study scientists from Boston University School of Medicine supplemented 36 subjects who had coronary artery disease with ALA and ALCAR or an inactive placebo for 8 weeks. Then both groups were switched to the other agent (a crossover study) for an additional 8 weeks. If the patient had normal blood pressure the supplements had a very mild tendency to lower systolic blood pressure (the top figure in a blood pressure reading). However if they had either high blood pressure or metabolic syndrome their was a significant contribution to lowering systolic pressure by 9 points on average. The study is published in the April 2007 issue of the Journal of Clinical Hypertension.

Nutrients help Peyronie?s disease; Potaba and ALCAR

In Peyronie?s disease there is a build up of fibrous tissue in the male organ occurring in almost 10% of all men. A number of drugs and some supplements are used to help treat it. Placebo controlled studies indicated that only Potaba (the prescription version of the B-complex vitamin PABA) and ALCAR (Acetyl-L-Carnitine) treat it successfully. Potaba may decrease plaque size and curvature of the organ while ALCAR may decrease erection pain and inhibit worsening of the condition. Other treatments are injection of interferon directly into the organ (many side effects including flu-like symptoms and fatigue) or surgery. The research review was performed at the Department of Urology at Tulane Health Sciences Center in New Orleans and is published in the journal Drugs, 2007;67(4).