Both Pomegranate Extract and Genistein kill breast cancer cells, and they work even better together
January
24,
2006
Previous studies have demonstrated the anticancer effects of Pomegranate Extract and Genistein on
cell lines from different cancers. Human breast cancer cell lines were exposed to both Pomegranate
Extract and Genistein for 24 hours. Both Pomegranate Extract and Genistein significantly inhibited
the growth of breast cancer cells. Both had significant cytotoxic effects on breast cancer cells
ultimately causing the death of the cancer cells. Adding the two together significantly increased
their ability to cause the death of breast cancer cells. The study was performed at Florida Atlantic
University, Davie, Florida, and is published in the Winter 2005 issue of the Journal of Medicinal
Food.
This is a much more useful study than is readily apparent. The COX-2 enzyme is active in many
diseases. It is linked to decreased survival in cancer and increased ability of a tumor to
metastasize because COX-2 and PGE2 allow the tumor to create its own transport system of blood
vessels. COX-2 is active in cancers of the breast, colon, skin, bladder, esophagus, and pancreas.
COX-2 plays a major role in inflammation and it also causes brain damage in Alzheimer's disease.
COX-2 is involved with menstrual pain and other inflammation related conditions, but its best known
role is in arthritis and joint damage.
Green Teas major Polyphenol, EGCG, strongly inhibits the development of prostate cancer in high risk men
Recent studies show that men with high grade prostate intraepithelial neoplasia (HG-PIN) will
develop prostate cancer within one year. In this study 60 men with HG-PIN were placed on a Green
Tea Polyphenol product consuming 200mg of Green Tea 3 times a day (with a EGCG content of 51.88%
and a total Green Tea Polyphenol content of 75.7%) in a double-blind, placebo-controlled random study.
After one year, 9 of the men placebo developed prostate cancer (a 30% incidence) while only one man
on the Green Tea Polyphenols developed prostate cancer (3% incidence). The study is published in the
January 15th, 2006 issue of the journal Cancer Research.