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Astragalus Inhibits Herpes Virus

Feb 03, 2005

The oral herpes simplex virus type 1 (HSV-1) typically infects the area around the mouth and it is a lifelong nuisance. In this study scientists added the herb Astragalus membranaceus to HSV-1 infected cells. Astragalus had an obvious and strong effect on the herpes virus and was safe lacking toxicity. The study was performed at the department of pharmaceutics, General Hospital of PLA, Beijing.

Beta-Sitosterol plus Resveratrol Inhibit Prostate Cancer Cell Cycle

Prostate cancer cells were supplemented with beta-sitosterol and Resveratrol either alone or together. Adding the phytochemicals together gave the best result in inhibiting prostate cancer. They increased levels of prostaglandins that regulate cell growth, and they inhibited the growth of the prostate cancer cells. They were able to induce prostate cancer cell death and they interfered with the growth of the cells at different points in their growth cycle. The research was performed at the School of public Health and health professions, State University of New York at Buffalo and is published in the March 2005 issue of the journal Prostaglandins, Leukotrienes and Essential Fatty Acids.

Chemotherapy Worked Modestly Better with Mega-Dose Antioxidants for Dangerous Lung Cancer

  • In vitro and animal studies suggest improved antitumor effects with chemotherapy and antioxidants.
  • In this study, researchers used mega-doses of antioxidants in conjunction with chemotherapy for patients with advanced non small cell lung cancer (stage IIIb, and stage IV NSCLC). 72 patients received the chemotherapeutic regimen of paclitaxel and carboplatin alone, while 64 patients received the paclitaxel and carboplatin along with vitamin C 6,100mg a day, synthetic vitamin E 1050mg a day, and beta-carotene at 60mg a day.
  • The overall response rate to chemotherapy alone was 33%, with 24 patients showing a partial response and no patients showing a complete response.
  • The overall response rate to the chemotherapy-antioxidant combination was 37% with 24 patients showing a partial response and 2 patients showing a complete response.
  • The median survival time for chemotherapy alone was 9 months and for the chemotherapy plus antioxidants was 11 months.
  • The survival at one year was 32.9% for chemotherapy alone, and 39.1% for combination chemotherapy with antioxidants. At two years it was 11.1% (chemo alone) and 15.6% (chemo with antioxidants).
The research was performed at the Department of Radiology, School of Medicine, University of Colorado Health Sciences Center in conjunction with the Department of Oncology, Institute Rotary Cancer Hospital in New Delhi and is published in the February 2005 issue of the Journal of the American College of Nutrition.