Antioxidant vitamins may protect women fromcancer of the uterus
Increased intakes of Vitamins C and E and beta-carotene may
reduce the risk of cancer of the uterus, according to a new review and
meta-analysis of the science to date. Writing in Cancer Causes and
Control, US scientists report that for every 1,000 microgram increase
per 1,000 calories of diet for Beta-Carotene there was a 12% reduction
in the risk of endometrial cancer.
Similarly, for every 50 milligram increase per 1,000 calories
for Vitamin C there was a 15% reduction in the risk of suffering with
endometrial cancer, and for every 5 milligram increase per 1,000
calories for Vitamin E the risk of endometrial cancer was reduced by
9%. Endometrial cancer is the fifth most common cancer among women
worldwide - around 7,000 American women die from the disease annually.
The results are based on data from 12 case-control studies, and intakes
from supplements were not considered by the researchers, led by Elisa
from the Cancer Institute of New Jersey. Commenting on the potential
mechanism, the US-based researchers noted that antioxidant vitamins may
reduce the risk of cancer by limiting oxidative damage to DNA.
In an editorial comment in the Journal of the American Medical
Association, Peter Gann, MD, ScD, from the University of Illinois at
Chicago, said: “...single-agent interventions, even in combinations,
may be an ineffective approach to primary prevention in average-risk
populations.” Bandera worked in collaboration with scientists from the
University of Medicine and Dentistry of New Jersey, the American Cancer
Society, and Kaiser Permanente. The study is published in the July 2009
issue of the journal Cancer Causes and Control.