Acetaminophen and Placebo Equal for Knee Arthritis in New Study

Aug 13, 2004

Acetaminophen is widely prescribed for pain due to osteoarthritis of the knee. A spokesman for the American College of Rheumatology says there have been few clinical trials comparing acetaminophen, the active ingredient in Tylenol, to placebo for osteoarthritic pain. In the new study of 779 patients with osteoarthritis of the knee, giving 4 grams a day of acetaminophen for 6 weeks gave pain relief to the same number of individuals as inactive placebo - 52.6% for acetaminophen and 51.9% for placebo, however the degree of pain relief was better for acetaminophen. The study is published in the August edition of the Annals of the Rheumatic Diseases.

Glycation Damages Cells

Glycation is the burning of protein by sugars. This causes a massive amount of free radical damage and leads to destruction and deterioration of tissues. Glycation causes a mixed bag of cellular-free radical damage and it is very destructive. This glycation and its resultant damage is increased in diabetes, kidney failure and aging. It turns out that damage to small blood vessels correlates with glycation and advanced glycation end products (AGES) and this is a major cause of diabetic retinopathy and kidney damage. This occurs because of a trigger of local and continuous inflammation in these tissues by AGES. This also leads to the vascular damage seen in diabetes. The study is published in the current issue of Circulation research, a Journal of the American Heart Association.

Dairy intake tied to lower body fat in girls

Researchers studied girls 9-14 years of age for their dairy consumption and calcium intake respectively.The findings pointed to the girls that consumed dairy had a lower abdominal adiposity as compared to the other group of girls that consumed less dairy products. One reason may be due to calcium effecting hormones that help store calories as fat. The researchers found the average daily calcium intake fell short of the recommended level for children to be 736 mg versus the recommended amount 1,300 mg a day. The study was published in the August 2004 issue in the Journal of Nutrition.

Commentary by Leonore Salvia, BS.RDE.

Calci-Chews or CalPlus would be an excellent addition to a vitamin regimen for girls age 9-14 years of age to prevent childhood obesity and help them reach peak bone mass for later years.